dewormer – Imovec™, Stromectol™

You’ve probably heard by now how all us rednecks are turning to a “dewormer” to protect us against COVID (or its progeny) or even treat an established infection.  Of course, disaster has ensued, but don’t believe those reports of an epidemic of dewormer overdoses, as they have been debunked (1).  But what about this anyway?  The dewormer – ivermectin – is a drug approved by the WHO and FDA for treatment of parasitic infections.   It’s been on the market since 2006.  The docs who developed it – William C. Campbell, Satoshi Ömura, and Youyou Tu – won the Nobel prize for Medicine and Physiology in 2015.  It’s a huge drug in the 3rd world, as it’s active against so many of the creepy crawlies that can make life miserable there: river blindness (onchocerciasis) and strongyloidiasis (an intestinal parasite with systemic effects) and even scabies and lice.  Such are the protective effects of this drug against these diseases in many African countries they take it prophylactically.  In the U.S., use is mainly veterinary as a dewormer, hence the sobriquet.  Yet the drug has exhibited antiviral activity against a wide range of RNA viruses and some DNA viruses, for example, Zika, dengue, yellow fever, and others..  It has specific action against SARS-CoV-2 in vitro with a suggested host-directed mechanism of action blocking of the nuclear import of viral proteins.  It may also inhibit SARS-CoV-2n3CLPro activity (a protease essential for viral replication) and even compete with spike protein for binding to ACE-2 receptors (the initial step in viral infection) (2).

So does this stuff work?  You wouldn’t know it from activity of any American docs, or even from our Euro brothers and sisters.  In another example of outsourcing gone mad, you have to turn to the 3rd world, where no less than 24 clinical trials have been conducted on the efficacy of ivermectin in COVID infection (2.,3).  And guess what?  It works, across the board.  Prophylaxis and treatment.  Not all the trials were up to our prissy standards, but there they are: COVID + ivermectin > COVID only.  Let me have some of that stuff!

One of the most impressive “trials” was indirect, and based in Africa.  Not all African countries prescribe prophylactic ivermectin, but many do.  Look at this graph of COVID deaths in Africa and judge for yourself whether ivermectin might have an effect.

Merck, who still holds the exclusive patent on ivermectin, has priced ivermectin dirt cheap, recognizing that its customers in the 3rd world don’t have gold plated insurance or deep pockets.  100 12 mg tablets for scabies costs $2.90.

Here are some protocols about how to use this stuff, all courtesy of https://covid19criticalcare.com/wp-content/uploads/2020/11/FLCCC-Ivermectin-in-the-prophylaxis-and-treatment-of-COVID-19.pdf

Note that some additional nutraceuticals are recommended.

How to get his stuff?  Of course, your doctor can prescribe it.  Thusfar, the major medical societies and licensing boards that brought down the hammer on those who dared prescribe Plaquenil have not done so for ivermectin. I got my little bottle of veterinary ivermectin on Amazon for not much.  It sits in my fridge.

Just squirt enough to make 0.2 mg/kg (yes, there is some math involved) in some juice, and there’s your daily dose.  Unfortunately, Amazon has run out and doesn’t sell it right now.  You can get ivermectin online at www.AFLDS.com or www.DrStellaMD.com.  You can also go on-line to pharmacies outside USA.  Just search for “ivermectin on line”.

But how safe is this stuff?  To hear the MSM, we’re taking our life in our hands.  Google “ivermectin overdose’ and you’ll get some helpful references about chickens, pigs, and dogs.  A quite sober French pharmacologist has compiled an extensive review of the adverse effects of ivermectin (4).  There have been some deaths after taking ivermectin, but these were in patients with a heavy parasitic load. Other toxicities have been observed in lab animals, but none in humans.  The stuff is muy safe.

So get some of this stuff!  It may be your best bet to escape COVID.  Way better than that silly mask.  And any worms you happen to be harboring will just slide away.

References

1.         Davis J.  Ivermectin Hit Piece Debunked After Hospital Steps Forward with the Truth.  The Western Journal 9/6/21.  https://www.westernjournal.com/ivermectin-hit-piece-debunked-hospital-steps-forward-truth/?utm_source=Email&utm_medium=WJBreaking&utm_campaign=breaking&utm_content=western-journal&ats_es=d937b441d27be285460151f72946f5e9

2.         Bryant A, Lawrie TA, Fordham EJ. Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines. American Journal of Therapeutics, 28, e434-e460, July 2021. Am J Ther. 2021 Aug 18;28(5):e573–6. https://doi: 10.1097/MJT.0000000000001442. Epub ahead of print.

3.         Hill A, Garratt A, LeviJ, FalconerJ, Ellis L, McCann K, Pilkington V, Qavi A, Wang J, Wentzel H.  Meta-analysis of randomized trials of ivermectin to treat SARS-CoV-2 infection, Open Forum Infectious Diseases, 2021;, ofab358, https://doi.org/10.1093/ofid/ofab358

4.         Descotes J.  Expert Review Report.  Medical Safety of ivermectin.  MedinCell (France) https://www.medincell.com/wp-content/uploads/2021/03/Clinical_Safety_of_Ivermectin-March_2021.pdf

 

Published by rike52

I retired from the Rheumatology division of Michigan Medicine end of June '19 after 36 years there. Upon hitting Ann Arbor for the second time (I went to school here) it took me almost 8 months to meet Kathy, 17 months to buy her a house (on Harbal, where we still live), and 37 months to marry her. Kids never came, but we've been blessed with a crowd of colleagues, friends, neighbors and family that continues to grow. Lots of them are going to show up in this log eventually. Stay tuned.

2 thoughts on “dewormer – Imovec™, Stromectol™

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