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drugs

actually, those 95 authors did provide a table of the drugs they’ve tested which show promise against coronavirus. Here it is. I fear the structure of the table has not survived the paste. I refer the interested reader back to the URL in my last blog post. Take it as a demonstration of the amazingContinue reading “drugs”

Look out Mr. Corona, here comes Science

The latest piece of COVID-19 information circulating in my Division Monday was a pre-print of a manuscript submitted to Nature (perhaps the world’s most highly regarded scientific journal) regarding the results of a molecular tour de force investigation of COVID-19’s protein components and the human proteins with which they interact, examining properties of existing drugsContinue reading “Look out Mr. Corona, here comes Science”

Hands off My Plaquenil?

My young friend Jason, research superstar and damn fine doctor to boot (see “shameless plugs” 2/22/20), is married to Sara, a science writer. Sara has spent the last little while researching how the patients Jason and I look after see the new interest in one of their mainstay drugs – Plaquenil (hydroxychloroquine) – as aContinue reading “Hands off My Plaquenil?”

Treating COVID-19

On March 4th, in a 9 page (once translated) document, the Chinese Health and Public Health Ministry put out their 6th revision of its Guideline on Novel Coronavirus Disease (COVID-19) Diagnosis and Treatment. I put the full guidelines on my blog Thursday. Only 2 small sections mentioned anything about drug treatment. But they have foundContinue reading “Treating COVID-19”

How Plaquenil May Work

I struggled for 36 years in Rheumatology to figure out how Plaquenil works in our diseases, and never did. But I think I might understand, at least in part, how it’s working in its new role as our savior from Mr. coronavirus. It’s just a matter of simple chemistry. OHC (hydroxychloroquine: Plaquenil) accumulates in acidic intracellular organelles,Continue reading “How Plaquenil May Work”

The Chinese COVID-19 Guidelines March 4th

The Chinese Health and Public Health Ministry Guideline on Novel Coronavirus Disease (COVID-19) Diagnosis and Treatment (revision #6) was released in Beijing March 4th. The guideline derives from experiences in treating over 80,000 Chinese patients. The document has been translated from Mandarin and stealthily but broadly circulated for about a week. Dr. Ainlin Xu, anContinue reading “The Chinese COVID-19 Guidelines March 4th”

Plaquenil for corona

My Saturday post mentioned initial findings that the old anti-rheumatic drug Plaquenil (hydroxychloroquine) may have some significant activity against coronavirus. The Chinese Health Ministry guidelines on coronavirus have been stealthily and widely distributed. I saw both versions (translated and Mandarin) the same Saturday I made my post. The guidelines even made it to a GPContinue reading “Plaquenil for corona”

smokin’ corona

On my walk home from Kathy’s office this morning, I ran into 3 old girlfriends from work standing in front of the bus stop across from the hospital. They weren’t waiting for a bus. None had a job you could do from home (medical assistant X 2, check-in clerk) and yes plenty of patients wereContinue reading “smokin’ corona”

another funeral song

Just heard another song I want played at my funeral We’ll get up and do it again. Amen

testing

My dear former English teacher is a constant source of inspiration. She sent me an article about new drive up coronavirus testing in the San Mateo valley. I guess you just drive up, roll down your window, and stick your nose out to have it swabbed by the friendly health care worker in the window.Continue reading “testing”