Tonic?

After reading yesterday’s blog on corona, my high school English teacher Mrs. Pharriss was particularly taken by the part on possible treatment of the virus with Plaquenil (hydroxychloroquine), derived from quinine. She asked if tonic water might help. I have the answer. This is what I wrote back to Mrs. Pharriss.

Now you’re giving me math assignments!  The dose of quinine to treat malaria is 2-3 200-350 mg tablets 3 times a day.  Likely you’d want to achieve similar levels to kill coronavirus. That’s a daily dose range of 1200-3050 mg/d.  The FDA limits the concentration of quinine in tonic water to 83 mg/liter.  If you assume your quinine water is the strongest allowed by law (Schwepp’s, presumably), you’d have to down 4.4-11 liters, or 1.2-2.9 gallons, per day to achieve therapeutic levels.  If you had that nicely balanced with Tanqueray, you wouldn’t be worrying about Mr. coronavirus anymore. 

Published by rike52

I retired from the Rheumatology division of Michigan Medicine end of June '19 after 36 years there. Upon hitting Ann Arbor for the second time (I went to school here) it took me almost 8 months to meet Kathy, 17 months to buy her a house (on Harbal, where we still live), and 37 months to marry her. Kids never came, but we've been blessed with a crowd of colleagues, friends, neighbors and family that continues to grow. Lots of them are going to show up in this log eventually. Stay tuned.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: